As the "New Game" is selected, the lights turn on as Professor Oak introducing himself as well as the world of Pokémon. He explains that the world is inhabited by creatures known as Pokémon and that people use them as pets and for fights. After releasing an Eevee from its Poké Ball, he invites the audience to the world of Pokémon.
The scene changes to a battle between a Gengar and Nidorino that is being watched by Red in his room. His mother calls up the stairs to him and tells him that Professor Oak wants to see him in his lab. Excited by this, Red rushes out of his room, and in his haste, falls down the stairs. His mother asks him if he is alright and he quickly gets back up as he says he is fine. (In the English version, Red's mother advises her son to be more careful and Red promises) However he puts his cap back on, and runs over to Professor Oak's Laboratory. In front of the lab, Red meets up with Green (Blue in the English version), who is Professor Oak's grandson and Red's rival, who was also called down to the lab. They race in as Professor Oak greets them. He hands each of them a Pokédex, a high-tech encyclopedia of Pokémon, which he has been working on. He asks them both to fulfill his dream of making a complete guide on all Pokémon.
In addition to doing this, Professor Oak allows the boys to pick one of the three starter Pokémon: Charmander, Squirtle, or Bulbasaur. Green lets Red pick first. Though Professor Oak advises them both to think carefully before they choose, Red picks Charmander almost immediately. He explains that his father named him Red, and cites it as the reason he wanted his first Pokémon to be a Fire-type. Professor Oak asks Green if he is going to pick Squirtle for similar reasons, and while Green denies that he would pick his Pokémon for such a ridiculous reason, he chooses Squirtle anyway, solely because of its advantage over Red's selection. Professor Oak asks if they would like to nickname either of their Pokémon, but they both decline. Green starts to challenge Red to a battle, but then changes his mind, teasing that he wants his first battle to be memorable instead of against a novice like Red. This prompts Red to angrily argue that Green is just as much a beginner as he is, but Green argues that he has greater ambitions than Red. Green goes on to explain that he wants to be the greatest Pokémon Trainer in the world while promising to complete the Pokédex and exit the laboratory. Prof. Oak remembers he was also a powerful Pokémon Trainer. Red hears this and Red begins his journey shortly afterward.
Walking down the road, Red encounters a Pidgey. He sends Charmander out to battle it, but Pidgey overwhelms them both with a Gust attack, preventing Charmander from using Ember as ordered, and also flies off, evading the Poké Ball Red throws at it. Red sits down with Charmander and looks up Pidgey in his Pokédex, only to discover that the Pokédex does not register full data on a Pokémon unless he succeeds in catching it. However, his next battle against a Rattata is more successful, and he catches the Rattata. This is shortly followed by his catching a Spearow, a Caterpie, and a different Pidgey. The scene moves to him battling a Youngster Trainer in a forest. The Youngster sends out a Nidoran♀, and after Red states that he has never seen one before, he sends out Charmander, who knocks the opponent out in one hit. After attacking, Red tries to catch the Nidoran♀, but the Poké Ball is rejected. The Youngster accuses Red of trying to steal his Pokémon and calls him a thief, but Red attempts to explain the misunderstanding, and asks where he can catch his own Nidoran♀, and the Youngster points him in the right direction.
Red makes it close to Viridian City, where he runs into Green. Green challenges Red to a battle, and Red explains that his journey is not to make his Pokémon stronger, but rather just to complete the Pokédex. Green explains that in order to complete the Pokédex, Red will have to battle against strong Pokémon, and then teases him about having a good excuse to wimp out of battles. This angers Red, and Green states his opinion that Red is not confident that he can win, and adds that he will not lose to Red no matter what.
This convinces Red to accept the challenge, and the battle begins, Green sending out Squirtle, and Red sending out Charmander. Unknown to either of them, their battle is being watched from behind several trees by someone. Charmander starts by using Growl, which does not seem to faze Squirtle. Blue orders a Tackle attack, and Red tries to counter with Ember, but Squirtle dodges the move before slamming into Charmander. Red tells Charmander to use Scratch, but Squirtle pulls its head into its shell to dodge, and Charmander's claws strike the shell uselessly. Red orders another Scratch, but Green orders another Tackle, which Squirtle is able to pull off before Charmander can react, sending it flying back again. As Charmander struggles to get back to its feet, Red calls for an Ember, and Green orders Squirtle to use Bubble. The attacks collide, but Bubble overpowers the Fire-type move. Green asks Red if that's all he's got, and orders Squirtle to use Bubble again. It fires off multiple Bubble attacks, which Charmander manages to dodge. Red, however, tells Charmander to use Ember instead of running away, and as Charmander tries to comply with this, it ends up taking a Bubble attack. Before it can recover, Squirtle pins it to the ground, and on Green's orders, uses Bite. As Charmander thrashes about, trying to get away, Red notices the flame on its tail growing smaller, and hastily withdraws Charmander to its Poké Ball. Green withdraws Squirtle, and laughs about how weak Red was. He tells Red he might as well just go back to Pallet Town, and that he has no hope of completing the Pokédex.
Distressed by his defeat, Red sits down next to a lake and thinks to himself that he and Green should be at the same level, as they both started their Pokémon journey at the same time. Brock, who had been watching Red's battle with Green the entire time, states that Red is wrong, and that Green was the more experienced one. Red asks his name, but instead of answering, Brock asks if Red understands the types and characteristics of his Pokémon, and then explains to Red that he and Charmander are clearly not in sync. Red claims that to be a lie, but Brock goes on, pointing out that Squirtle responded quickly to Blue's instructions and dodged attacks using its own judgement.
He explains that Pokémon and their Trainers are connected, that Squirtle clearly recognized and trusted its Trainer's power, and that Pokémon will not connect with Trainers who have no power. As Brock says that a Pokémon's strength is proportional to its Trainer's power, Red nods in understanding, and then starts to walk away. Brock asks what he's doing, and Red explains that he intends to challenge everyone with Pokémon to battles. At this, Brock reminds Red how weak and hurt his Charmander already was, and urges him to take it to the Pokémon Center first. Then, he tells Red that if he wants to learn the basics of battle, that he should visit the Gym Leaders, explaining that they are experienced with Pokémon battles, and that Red could learn a lot from them, but also warns Red that they are only willing to battle Trainers who are willing to learn. He walks away, telling Red to think about what battling Pokémon is really all about.
Red goes to the Viridian City Pokémon Center and gets his Pokémon healed. While the nurse is looking after them, he calls Professor Oak, who reminds him that if he catches a Pokémon while having six on hand, it would get sent to the PC. Then, Professor Oak asks what is wrong, stating that Red sounds a little down, but Red assures him that it is nothing. Professor Oak then reminds Red that his is a long journey, and to not push himself too hard. After the call, the nurse calls Red over and hands him back his Poké Balls, confirming that his Pokémon are all fighting fit. Later on, Red arrives in Pewter City, and in the Pewter City museum, Red overhears two people talking about the Pewter City Gym Leader, Brock. He decides to head to Pewter Gym and challenge the Gym Leader. When Red gets there, however, two people tell Red that he is light years from facing Brock, an opinion only reinforced for them when Red reveals he had only been a Trainer for five days. Then, from behind, Brock tells them that he invited Red, to their initial disbelief. Red is initially shocked that the man he talked to back near Viridian City was the Pewter City Gym Leader. Brock then asks Red if he has an answer to the question that was asked earlier. Red says that he does not, but then explains that that is because he did not have an answer for why he came to the Gym. Intrigued by this response, Brock agrees to battle Red.
As the two enter the main area of the Gym, Brock asks Red if he has any badges. Upon Red's confirming that he has none yet, Brock goes over to a wall, which opens up, revealing a tray containing six Poké Balls. He takes two of them, and tells Red that he will battle him using two Pokémon, which seems to surprise Red. Brock then throws one of the balls, explaining that his specialty is battling with Rock-type Pokémon as a Geodude comes out. Red responds by sending out Charmander, and the battle begins. However, Charmander's Ember and Scratch attacks do next to nothing to Geodude who, to Red's confusion, has yet to fight back. He decides to wait to see what Geodude may do, which proves to be a mistake, as Geodude's Tackle causes major damage.
Red orders several Scratch attacks, all of which do almost nothing to Geodude, and Brock claims that Red doesn't seem to have learned anything. He recalls asking Red whether he knew anything about the types and characteristics of his Pokémon, and explains that Fire-types are weak to Rock, and that only using Charmander puts him at a disadvantage against Rock-types. Red does not understand what Brock is getting at, so he goes on to explain that Red is allowed to switch Pokémon in a battle. Red withdraws Charmander and sends out a Nidoran♂, who knocks out Geodude with Double Kick. Brock withdraws Geodude, and sends out his second Pokémon, an Onix. Red is surprised that he is facing another Rock-type, and Brock reminds him that his specialty is Rock-types. Red orders a Double Kick, and Brock calls for Bide. He then explains that when using Bide Onix cannot attack until it has been attacked twice. Red is surprised by this, and voices the possibility of Onix being defeated with two attacks.
Brock replies that he believes in Onix, and is confident that two attacks would not be sufficient to take it out. Red orders another Double Kick, but it is not enough to knock out Onix. Onix then unleashes Bide, and knocks Nidoran out in one blow. Brock explains more about Bide, informing Red that it allows Onix to deal twice the damage it has taken. Red sends out Spearow, but Onix knocks it out almost immediately. Red withdraws Spearow and sends out Rattata, only to have it meet the same fate. He realizes that Onix is too fast, and sends out a Metapod, ordering it to use String Shot. Metapod ties Onix up with String Shot, but Brock bellows that the attack will not work, and Onix manages to snap off the strings. The two people from the entrance of the Gym remark on how serious Brock is getting. Red calls for another String Shot, but Onix uses Tackle and knocks Metapod out. Red withdraws Metapod and then, claiming to only have one more Pokémon, sends Charmander back out. By this point, both Brock and Red are starting to pant, and Brock asks Red if he is starting to understand what battling is about.
Red thinks about this, noticing that he is getting exhausted and that he does not know why, and that he feels as though he is also taking damage. And then it occurs to him that Pokémon are not tools for battle, but rather partners, that he and his Pokémon are battling together. Brock gives a small smile as Red explains what he has realized, and then points out that Onix and Charmander are almost out of HP, and that the next attack would decide the battle. He orders Onix to use Tackle, and Red tells Charmander to use Scratch. They attack simultaneously, their Speed apparently identical; Onix faints. Though the two people are confused about this, they notice something floating to the ground from where Onix was when Brock withdrew it--a single strand of String Shot. Brock then reveals what happened: he thought that Onix had torn off all of the strings, but it had in fact missed one, which was sufficient to make its attack just a split second too late. He gives Red a Boulder Badge and TM34 (Bide). Later on, after Red leaves, one of the people watching the battle asks Brock why he accepted Red's challenge, and Brock reveals that Red's response to his question had intrigued him.
The scene changes to Professor Oak's lab. One of Professor Oak's assistants asks him why he chose Red. He replies that although Red is clumsy, ever since he was a young boy he has hated to lose, and that Red is honest and will learn from others around him and grow stronger. He then says that he hopes Green will grow along with Red, because he sees that Green is he is too experienced and arrogant. Red runs off, promising to get his Pokémon stronger to complete Prof. Oak's wish to complete the Pokédex. After an hour and 24 minutes, Red collected 10 Pokémon and one badge, before it is being saved.
Continuing from Brock's defeat, Red managed to obtain a Magikarp for 500 pounds, defeated a Super Nerd at Mt. Moon (who held two fossils), even managing to defeat a member of "Team Rocket", who gave Red the stolen TM. Red also managed to defeat Misty from Cerulean Gym, obtaining the Cascade Badge. In addition, Red's Charmander evolved into a Charmeleon- Red obtained an Old Rod from a fisherman, a Hidden Machine, HM01 (Cut) from a sick captain and the Thunder Badge from Lt. Surge of Vermilion City, as well as a bike, using the voucher from the Pokémon fan club chairman. Currently, Red has passed through the Rock Tunnel to Lavender Town. As Red has Nurse Joy heal his Pokémon, he hears reports from townsfolk about the Pokémon Tower. Red asks the locals, who reply a ghost was seen at the tower. The tower is actually a graveyard for Pokémon and people around the world come to pay their respects at it. The woman points out the tower, while the man clarifies the ghost is a Pokémon.
Red admits he does not believe in ghosts, but the woman asks is the white hand behind his shoulder fake as well. Red is surprised and turns around, but sees nothing. Red goes to respond, but notices these people are gone. Nurse Joy reports to Red his Pokémon are healthy and fit. Nurse Joy, feeling Red is going to the tower to pay the respects, advises him to go to the Pokémon House first. Red enters the House and a girl comes. Red asks what is this House about and the girl replies it is a house for orphaned or abandoned Pokémon. The girl takes Red inside, showing many Pokémon that are taken care of, like Growlithe, Vulpix or Oddish. The girl advises him to talk to Mr. Fuji, the founder of the House. The girl lets Red know there are some people that think of Pokémon as tools for battle, hence why Mr. Fuji remodeled his house to let the Pokémon live in. This is why many townsfolk have helped Mr. Fuji to maintain the Pokémon. The girl introduces herself as Reina, as does Red. Red notices all Pokémon are friendly, but finds a shy Cubone. Reina tells Cubone is a baby and is nervous when someone is around, except Mr. Fuji.
Reina tells Red Cubone was nearly captured by Team Rocket. The grunts went to capture Cubone with a net, but were hit by a Marowak. Cubone escaped, while the grunt extended his rod and attacked Marowak. That was the day Cubone lost its mother, as well as the day when Mr. Fuji found Cubone and adopted it. Red is frustrated such an organization is capable of such acts. Red thanks Reina for showing him around and would like to meet Mr. Fuji. Reina replies Mr. Fuji knows a lot about Pokémon, giving Red the chance to find more data for the Pokédex. However, a man comes in, reporting Mr. Fuji went to the Pokémon Tower yesterday to confront Team Rocket. The man reports Team Rocket came in one day and made the base on the top floor. Worse yet, the grunts stop anyone trying to enter, even if to pay respects inside the tower. A woman reports she saw a ghost; one night, when Team Rocket was not on patrol, she entered the tower and found a ghost, who yelled at her to leave the place.
Reina proposes they should go in and battle Team Rocket. Others disagree, for Team Rocket grunts are quite strong and there is a ghost inside. Reina reminds them Mr. Fuji is imprisoned there and went there to get rid of the Team Rocket grunts. The people think they'll let Mr. Fuji go, in some time. Reina is frustrated, so Red decides to go in. The people remind Red that he is a child, and even the adults did not have the power to attack. Red shows them the three badges he obtained, confident in his skills as a trainer, both for Mr. Fuji and the Cubone. Blue watches this and plans on attacking Team Rocket before Red does. During the night, Red comes to the tower, admitting it is even scarier than he thought. He uses the flashlight to go into the tower and, by surprise, finds a woman. The woman tells him she is no ghost, for she wanted to see her Nidoran. She thinks Red came here to pay the respects, though he asks isn't the woman scared. The woman replies she isn't, since the ghost appears in upper levels.
Green also wanders the halls, thinking Team Rocket made up the story of the ghost to chase people away. Green climbs up the stairs, thinking the people of Lavender Town will remember him well to defeat Team Rocket. The grunt tells others there is supposed to be a real ghost Pokémon inside the tower, and it isn't a ghost-type. The other grunt dismisses that, knowing they can count on the Silph Scope to identify ghosts. Green climbs up and finds the ghost of the tower. The ghost yells to him to get out; Green screams and runs off. The grunts hear that and one goes off to find what happened. Blue screams and bumps into Red, warning him about the ghost. The ghost appears, making Red realize ghosts exist. However, unlike Green, Red chooses to fight, sending a Charmeleon. Green sneaks off and climbs up, but encounters the Team Rocket grunt and sends Wartortle to battle him.
Cubone tackles the gate and Reina lets Cubone out, who runs off. Charmeleon uses Scratch, but the ghost still remains. Red sees no attack can hit the ghost. Blue comes down and throws him a Silph Scope to use. Cubone runs up and Red puts on the Silph Scope, identifying the ghost to be Marowak, Cubone's mother. Marowak warns Red he shouldn't get close to the men. Red calls Charmeleon back, while Cubone comes and hugs Marowak. Marowak hugs Cubone and floats away. Blue leaves, seeing Red can handle other things. Red visits the grunts, throwing them the Silph Scope. Cubone is enraged at these grunts, but Reira restrains it, for it is too weak to handle them by itself. The grunt sends Koffing against Red's Jolteon. Koffing tackles Jolteon, who uses Quick Attack. Koffing uses Smog, covering the field with the cloud. Cubone releases its bone, using Bonemerang to clear the the field, allowing Jolteon to use Thunderbolt. Koffing is defeated, so the grunts retreat, promising to pay back Red for defeating them.
Red and Reina search and find Mr. Fuji tied up. Red introduces himself as he unties Mr. Fuji, who sees Cubone has calmed down after Marowak's spirit passed on. Next day, the people come to pay their respects to their Pokémon, while others tend to the Pokémon House. Mr. Fuji thanks Red, for Cubone also opened up to other people. Mr. Fuji remembers Red is on a project to complete the Pokédex. He advises his quest will fail if Red will not show love to his Pokémon. However, to help Red out, Mr. Fuji gives him a Poké Flute, an instrument that can awaken asleep Pokémon, as well as a box. Inside the box, he finds two gems, which Mr. Fuji thinks Red will think of how to use them. Red closes the box and rides off on his bike, bidding farewell to the townsfolk. After a while, Red stops, as Green, sitting on a tree, thinks Red owes him for Green gave him the Silph Scope to identify Marowak. Red reminds Green was the one that wanted to leave and flee the tower. Red grins and rides off, as Green claims he never said that.
With three badges and 45 Pokédex entries, the file is saved at 11 hours and 22 minutes.
Continuing from 15 hours and 34 minutes, Red managed to obtain two badges and record 65 Pokémon. Indeed, Red managed to defeat Erika and her Vileplume in Celadon City, earning the Rainbow Badge. Later on, Red managed to chase a Team Rocket member and find their secret hideout, as well as meeting the leader of Team Rocket. Afterwards, Red played his Poké Flute to awaken Snorlax, meeting with the fisherman's brother and earned the Super Rod (even catching a Psyduck with it), managing to defeat Koga and Weezing at the Fuchsia City to win the Soul Badge and having his Charmeleon evolve into a Charizard. Currently, Red is in Saffron City at the Silph Co. headquarters, where he encounters Green. Soon after, Green and Red rescued a woman, who was chased by Team Rocket and the three hid into the woods. The woman introduces herself as a secretary, reporting the president has been booted out and the company taken by Team Rocket.
The secretary reports Team Rocket is after the Master Ball, a Poké Ball that can catch any Pokémon possible. Despite it being a prototype, the Master Ball is sought out by Team Rocket, who threatened the employees to perfect it. Worse yet, they use wild Pokémon in the experiments, some of which are too exhausted. Green fears Team Rocket may misuse the ball and start selling off the Pokémon. The secretary reports the president entrusted her with the message to gather help from outside Silph Co. to stop this threat, since the president is being watched closely. She goes to report to the police and limps off, thanking Red and Green for saving her. They sneak, but find the grunts at the police station. Instead, Red asks Green to take the secretary to Celadon City and make the report there. Green refuses, wanting to focus on training to become the Pokémon League's Champion.
Red is angry and grabs Green, reminding him Team Rocket is out there and he cannot be called a Pokémon Trainer if he does nothing. Green is forced to take the woman, while Red plans on storming the Silph Co. Green is shocked Red would do that, but Red replies the Pokémon would still suffer if he didn't go in there. Red is angry, wanting Team Rocket to pay for their crimes. Red frees the wild Pokémon and the scientists, one of which gives Red a Lapras, so he can travel over the sea. Red barges in into the office and finds the president, a grunt and the boss of Team Rocket. The man tells Red has forced his way into the hideout, just in this moment he is discussing business with the president of Silph Co. Red admits the police are on their way to the hideout, but the boss commends him for bypassing the security and freeing everyone, even ruining the plans of Team Rocket. The grunt tells the boss, Giovanni, it is time to leave. Red plans he will stop the plans of Team Rocket every time.
Giovanni feels displeased and takes a Poké Ball. The grunt asks is it wise to waste time on a boy, but Giovanni replies it is more of a nuisance. Red sends Charizard and Giovanni Nidoqueen. Nidoqueen uses Double Kick, hitting Charizard and slamming it through the walls. Giovanni thought Red would be more of a challenge. Charizard uses Flamethrower, but is stopped by Nidoqueen's Surf. The attack causes a blackout in the tower. After the attack, Giovanni thinks this was a waste of gift to send out the very best, Charizard, who was easily defeated. Giovanni considers Red lucky he came here, but is asked why is he doing all this. Giovanni replies to Red Pokémon are business and business needs sacrifices. Red disagrees, claiming they are friends. Giovanni points out his friend suffered during the battle and has been defeated. Giovanni leaves on his helicopter, doubting Red will understand what Giovanni hopes to achieve. Since the police came too late, Team Rocket fled, though the development of the Master Ball was postponed.
Red, however, focused on other things. He managed to meet Sabrina and her Alakazam, defeating them and winning the Marsh Badge. Soon after, he challenged the dojo of the Karate Master, who let Red choose a Hitmonlee or Hitmonchan. Sailing across the sea on his Lapras, Red arrived to Cinnabar Island and visited the Pokémon Mansion. He found nothing, but old diaries, mentioning they found a new Pokémon deep inside a jungle. Soon after, he defeated the Gym Leader, Blaine, and his Arcanine, winning the Volcano Badge. Among the locals, Red heard there is the Viridian City's Gym, which was closed for a while, but was recently re-opened. Red rides off on his bike, deciding to challenge this strongest (eight) Gym Leader, thinking he will learn much from him. After arriving, Red meets up with Blue, who thinks Red is slow. Green shows he earned the Earth Badge, as he claims it was easy for him and walks away. Red comes to the Gym, but hears the Gym Leader has moved away for a moment.
After a while, Red enters the Gym and encounters Giovanni, who admits he is the Gym Leader. Red realizes this entire Gym is another Team Rocket base. Giovanni goes to take some Poké Balls, knowing Red will take up the challenge. Red refuses to believe Giovanni is the Gym Leader, for all other Gym Leaders, despite their different personalities and tactics, loved their Pokémon and would never claim Pokémon as tools for business. Giovanni grins, asking if Red would still battle. Red accepts, but reminds Giovanni he is fighting an enemy, not a Gym Leader. Giovanni admits yesterday, an arrogant boy arrived, but managed to defeat all of Giovanni's Pokémon. Since he fights Red, Giovanni uses two Ultra Balls instead. Giovanni feels there is something about Red that makes him almost lose control. Giovanni sends a Rhyhorn, intending on defeating Red. Red sends a Victreebel, so Giovanni remarks Red relies on the type advantage, rather than Charizard's brute strength.
Victreebel uses Razor Leaf, but is defeated by one Horn Attack from Rhyhorn. Giovanni knows Red's strategy to end this battle quickly, but it won't work. Red calls Victreebel back and sends Kabutops. Kabutops uses Slash, hitting Rhyhorn, who uses Take Down. Kabutops uses Hydro Pump, but is countered and defeated by Rhyhorn's Thunderbolt. Red sends Snorlax, who uses Hyper Beam, but misses and is defeated by Horn Drill. Giovanni is not pleased that this were Red's powerful Pokémon. Red sends Jolteon, making Giovanni surprised, for electric-types are weak against Ground-type Pokémon. Giovanni is disappointed, but feels some frustration towards the boy. Jolteon leaps to use Double Kick, but is defeated by Thunderbolt. Red wonders how could Jolteon be defeated that easily and is told Giovanni's Pokémon's level tops Red's Pokémon's. Giovanni wonders which Pokémon will Red use - Charizard or some other trump card.
Red sends a Hitmonlee. Giovanni remarks it is a fighting-type, but feels the battle quite alive and intense. Hitmonlee uses Rolling Kick, hitting Rhyhorn, who retaliates with Horn Attack. Giovanni feels this battle reminding him of one a long time ago. Using High Jump Kick, Hitmonlee hits Rhyhorn, who uses Horn Drill. Repeating the same moves, Rhyhorn and Hitmonlee exchange attacks and defeat each other. Both trainers call their Pokémon back. Giovanni knows Red will use Charizard, while Giovanni warns him he'll use Rhydon, making Charizard a no match to it and making it a big mistake. However, Red admits he wanted Charizard to be his last Pokémon, to prove love for it is not meaningless. Giovanni is angry and promises to crush Red's pride. Red knows well the Gym Leaders he defeated love their Pokémon and the Gym Badges are the proof of that. Red points to Giovanni Charizard is the proof he came far to here. Giovanni studies Red's moves, quite surprised and remembers this passion, for he also had a Charmander once. However, he does not know why this passion changed, seeing Pokémon as tools for business.
Giovanni sends Rhydon, thinking he may have been like Red. Charizard starts with Fire Punch and Rhydon with Ice Punch. Both exchange blows and hit each other. Charizard uses Mega Kick, but misses and gets hit by Fury Attack, slamming Charizard to the wall. Rhydon goes to finish Charizard with Horn Drill, though Charizard uses Seismic Toss, dodging Rhydon, grabbing and slamming it to the ground. Rhydon is defeated, making Red and Charizard as the winners. Giovanni admits he never'd thought Charizard is raised that well to defeat Rhydon. Giovanni presents the Earth Badge, but Red refuses a badge from the leader of Team Rocket. Giovanni admits Red does not anger him anymore and gives order to his grunts to send word Team Rocket is disbanded. Giovanni gives Red the Badge, reminding he gives it out as a Gym Leader who enjoyed this intense battle. Red is glad and takes the badge.
Giovanni warns Red to complete the Pokédex, he needs to be the strongest trainer around. Such a task can only be completed by becoming the Champion of the Pokémon League. Red leaves, while Giovanni hopes Red can achieve what he did not. Giovanni wants to change his life to love and trust Pokémon. Red cycles off, promising to find a way. The file is saved at 21 hours and 18 minutes. Red managed to obtain all Badges and record 99 Pokémon.
After 23 hours and 2 minutes of gameplay, Red, who has collected all badges and recorded 113 Pokémon, has arrived to the Pokémon League's Victory Road. After crossing the path, he challenges the Elite Four. Lorelei's Dewgong uses Aurora Beam, but misses Jolteon. Soon after, Red's Scyther dodges Bruno's Onix's attack, while Dodrio strikes, but gets through Gengar, who is incorporeal, so tries with Drill Peck. Eventually, Lapras attacks Dragonite with Ice Beam, defeating it. Lance is on his knees, seeing how Red is powerful. Lance commends him on the success, but tells to become the Pokémon Champion, Red needs to defeat the current Champion. Red steps through the door and encounters his rival, Green. Green laughs, for Red managed to come here. Green lets Red know he was always one step ahead of Red. Green has searched for an ultimate team and most powerful Pokémon, hence why he stands here as the most powerful trainer in the world.
Jolteon uses Thunder, but Pidgeot flies up, evading the attack. Scyther tries to cut through Alakazam, who blocks the attack. Red's Lapras fought against Rhydon and Arcanine, while Dodrio and Persian fought against Green's Exeggutor. The battle was long and intense and when Green sent his Blastoise, it knocked out Red's Persian and Jolteon, defeating them easily. Blue thinks Red cannot defeat him, no matter how much Red tries. Red sends Charizard, reminding Green of their very first battle, hoping this time the battle will be more challenging. Charizard uses Mega Punch, hitting Blastoise, who retaliates with Hydro Pump. Charizard is seriously hit, but manages to withstand the attack. Charizard uses Fire Spin, engulfing Blastoise, who dismisses the attack. However, Charizard uses Fire Blast, defeating Blastoise. Green calls Blastoise back, while Red praises Charizard, as they won the match.
Green is surprised he lost against Red, since he was a Champion for a short time and gave his best to defeat Red and failed. Green is somewhat surprised, as he raised his Pokémon perfectly. Still, he admits Red is the new Champion. Prof. Oak appears, congratulating Red on becoming the new Champion, as he had truly the skill to become one. Oak admits when he heard Green was the new Champion, he came from Pallet Town, but saw Red defeated him. Green is frustrated, thinking he was just unlucky this time. Prof. Oak scolds Green, reminding he needed to put some love and faith into his Pokémon. Since Red is the new Champion, Prof. Oak opens a room, the Hall of Fame, where the records of all past Champions are written. Red places his Poké Balls into the slots, which are scanned and recorded, along with Red, on a picture. Red wonders if it is okay to be and remain a Champion and is reminded he fought hard and bravely to achieve the title. The file is saved at 24 hours and 13 minutes.
However, the journey is not yet over, for it continues on to complete the Pokédex. After battling a Fearow, Red catches an Arbok with a Great Ball, then travels with Lapras to catch a Tentacool, as well as finding a Pikachu in the forest. In the Safari Zone, Red wonders either to throw a lure or a stone to Chansey. Chansey flees, but Red manages to catch her as well. Red also strived for legendary Pokémon, having Rapidash battle Articuno, Tauros against Zapdos and Charizard vs. Moltres. Red returns to Prof. Oak's lab, but does not see the professor. After being told by Oak's assistant what happened, Red rushes into the room, finding Prof. Oak tending to an injured Blue. Prof. Oak calms Red down, while Green replies he was battling a wild Pokémon in Cerulean Cave. The Pokémon blasted Blastoise away onto Gren, even crushing his Pokédex. Red offers to give Green his own Pokédex to let Green show what Pokémon was that. Red also admits he caught 149 Pokémon, making Prof. Oak immensely pleased his dream to have data about all Pokémon is here. Green also wishes he could've caught that wild Pokémon to complete the Pokédex.
Green remembers the wild Pokémon used Psychic and Barrier. Prof. Oak checks through Red's Pokédex and finds a Slowpoke, a Slowbro, a Drowzee, a Hypno, an Exeggcute, an Exeggutor. Green asks Red are all these Pokémon he caught, for neither of them have attacked Green. Prof. Oak realizes this may be a new Pokémon they never saw before and asks of Red to go to Cerulean Cave and check it out. Green protests, as this Pokémon is too powerful, beyond means, even for Red to battle against. Red has a flashback, as if he read those words before. Green admits he heard of these reports and wanted to catch this Pokémon to defeat Red next time, but Green failed. Prof. Oak comes with Red to the lab, since he needs to equip himself properly. Mr. Fuji tends to a Vulpix and Reina comes, telling Mr. Fuji of a powerful Pokémon inside Cerulean Cave, which defeated a former Champion. Mr. Fuji asks what type it is and is told most likely a psychic-type. Mr. Fuji replies this Pokémon is still out there.
As Oak's assistant goes to check Red's Pokémon, Prof. Oak asks Red what are these stones about. Red does not know, since he never used them, but Mr. Fuji told him "he'll know". Prof. Oak is surprised to hear Mr. Fuji involved in this. Red fishes outside and concentrates on Green's words the "Pokémon's power was beyond even us". Red realizes someone wrote that in the journal at the Pokémon Mansion. Red reports this to Prof. Oak - the diary states when the research team went into the deepest parts of the jungle and found a new Pokémon, naming it Mew. Some days after, the team managed to create a new Pokémon, Mewtwo. However, Mewtwo was beyond them, as it was too powerful to be kept around. Prof. Oak believes those were notes of Dr. Fuji, who was a Pokémon researcher, who discovered the new species of Pokémon. However, he was soon dismissed, as he created an artificial Pokémon, likely Mewtwo. Oak believes the man that gave Red the stones was actually Dr. Fuji. At any rate, Prof. Oak studied the stones and the stone started to react to Charizard. Oak advises Red to have the stone held by Charizard, letting the other one kept to himself.
Red heads to Cerulean Cave, while Reina reports this to Mr. Fuji, who wanted to "catch that monster". Red has Lapras surf into the cave, encountering Mewtwo. Red sends Gengar to battle Mewtwo, while Reina fears for Red's safety. Articuno uses Blizzard on Mewtwo, who recovers and hits Articuno with a dark power. Mr. Fuji fears Red's Pokémon will be instantly defeated, but thinks there is one hope. Red sends Charizard, while Mr. Fuji feels the hope coming from Red gives the strength. Charizard uses Fire Blast, but is hit by Mewtwo's Swift. Mr. Fuji believes a power, from the Kalos region, will, through bonds of Red and Charizard, improve their power. Red leaps to have Charizard land safetly, who uses Slash, but Mewtwo protects itself. Charizard and Red are thrown into the water. As they fall down, Red feels no matter which attack they use, Mewtwo is just too strong. Red notices Charizard is still strong and ready to battle. Red swims to rescue Charizard, but sees the two stones are starting to resonate and glow. They touch each other, triggering the Mega Evolution.
Mewtwo turns around and sees Charizard, but looking very differently. This "Mega Charizard" uses Fire Blast, hitting Mewtwo badly. Red is thrilled Charizard has become so powerful and throws an Ultra Ball to catch Mewtwo. However, Mewtwo breaks out, angrier than ever. Mewtwo uses Swift, hitting Mega Charizard, who retaliates with the same move. Mega Charizard uses Slash, attacking Mewtwo, while Red senses Charmander within Mega Charizard, as it grew and came a long way towards here. Mega Charizard uses Fire Punch, hitting Mewtwo, who is bashed onto a rock and phases out. Red throws another Ultra Ball, managing to catch Mewtwo. Red is thrilled and amazed they caught Mewtwo. Mega Charizard is happy as well, who reverts to its original form. Red hugs Charizard for this great accomplishment. Played about 35 hours and 46 minutes, Red recorded 150 Pokémon.
At the lab, Red, Green, Prof. Oak and his assistant cheer, for the Pokédex has been completed. Green replies he should've caught Mewtwo instead and be the Champion. Red, however, realizes something and Professor Oak asks what he's thinking. Red explains that he just understood that Mewtwo was created from a Pokémon named Mew, which means that there is still one more Pokémon out there for him to catch. Everyone gasps at the revelation, and Red stands up, ready to start his search for the 151st Pokémon. Unnoticed by anyone, a Mew suddenly appears outside of the window. Apparently having heard Red's words, it smiles teasingly before flying away.
Difference Between the Japanese version and English version
- The timeline for all of the core series games prior to Professor Oak's introduction was removed from non-Japanese versions. It was re-added for the English dub's Hulu release, but not to the iTunes release.
- In the Japanese Version, while Red is in his room. His mother calls up the stairs to him and tells him that Professor Oak wants to see him in his lab. Excited by this, Red rushes out of his room, and in his haste, falls down the stairs. His mother asks him if he is alright and he quickly gets back up as he says he is fine. However he puts his cap back on, and runs over to Professor Oak's Laboratory. But in the English version, while Red is in his room. His mother calls him up stairs and tells him Professor Oak finished something important. Excited about this, Red rushes out of his room, and in his haste, falls down the stairs. Red's mother advises her son to be more careful. However while he puts his cap back on, Red promises and runs over to Professor Oak's Laboratory.
- In the Japanese version, Professor Oak instead asks if Blue is going to choose Bulbasaur as his starter Pokémon because its color matches his Japanese name, Green, but he says that he doesn't pick his Pokémon for "such a girlish reason", and instead chooses Squirtle to counter Red's Fire type. But in the English version, Professor Oak asks if Blue would choose Squirtle because its color matches with his name, to which Blue replies that he would never choose his Pokémon for "such a ridiculous reason", but still chooses Squirtle, due to its type advantage over Red's Charmander.
- In the Japanese version, Red had mentioned "Sepultra" as a possible nickname for Charmander. セパルトラ Sepultra is actually a nickname given to a Charmander seen in the back of the Japanese box of Pokémon Red and Green. But in the English version, when Red is pondering over the matter of giving his Charmander a nickname, no actual name suggestions are said aloud prior to Red's decision of leaving Charmander's name unaltered.
- In the Japanese version, when Charmander is bitten by Squirtle. His scream is high pitch. But in the English version, when Charmander is bitten by Squirtle. His scream is toned down.
- 4 (total)
- Junko Takeuchi as Red
- Takuya Eguchi as Green (known as Blue in the U.S)
- Katsuji Mori as Professor Oak
- Minoru Inaba as Mr. Fuji
- Yui Ishikawa as Reina
- Shinichiro Miki as Red's Charizard, Charmander, Charmeleon & Mega Charizard X
- ??? as Red's Jolteo
- Rikiya Koyama as Giovanni
- Tomokazu Sugita as Brock
- Tokuyoshi Kawashima as Lance
- Satsuki Yukino as Red's Mom
- ??? as Green's Squirtle
- ??? as Green's Blastoise
- ??? as Red's Nidoran
- ??? as Red's Rattata
- ??? as Red's Spearow
- ??? as Red's Victreebel
- ??? as Red's Kabutops
- ??? as Red's Snorlax
- ??? as Red's Hitmonlee
- ??? as Red's Lapras
- ??? as Red's Scyther
- ??? as Red's Dodrio
- ??? as Red's Gengar
- ??? as Red's Articuno
- ??? as Red's Zapdos
- ??? as Red's Moltres
- ??? as Red's Mewtwo
- Satomi Korogi as Mew
- ??? as Brock's Geodude
- Unsho Ishizuka as Brock's Onix
- ??? as Cubone
- ??? as Marowak
- ??? as Giovanni's Nidoqueen
- ??? as Giovanni's Rhyhorn
- ??? as Giovanni's Rhydon
- ??? as Young Giovanni
- ??? as Giovanni's Charmander
- Bryce Papenbrook as Red
- Lucien Dodge as Blue (known as Green in Japan)
- Kyle Hebert as Professor Oak
- Kirk Thornton as Mr. Fuji & Lance
- Christine Marie Cabanos as Reina & Mew
- Shinichiro Miki as Red's Charizard, Charmander, Charmeleon & Mega Charizard X
- ??? as Red's Jolteon
- Jamieson Price as Giovanni
- Johnny Yong Bosch as Brock
- Laura Post as Red's Mom & Marowak
- ??? as Blue's Squirtle
- ??? as Blue's Blastoise
- Cristina Valenzuela as Red's Nidoran & Cubone
- ??? as Red's Rattata
- ??? as Red's Spearow
- ??? as Red's Victreebel
- Lucien Dodge as Red's Kabutops
- ??? as Red's Snorlax
- unknown as Red's Hitmonlee
- unknown as Red's Lapras
- unknown as Red's Scyther
- unknown as Red's Dodrio
- unknown as Red's Gengar
- unknown as Red's Articuno
- unknown as Red's Zapdos
- unknown as Red's Moltres
- unknown as Red's Mewtwo
- unknown as Brock's Geodude
- Keith Silverstein as Brock's Onix
- unknown as Giovanni's Nidoqueen
- unknown as Giovanni's Rhyhorn
- unknown as Giovanni's Rhydon
- unknown as Young Giovanni
- unknown as Giovanni's Charmander
- Junko Takeuchi's first time being in the Pokémon series. She would later on play a young boy character in the Hoopa series.
- Although based on the first generation games, in episode 4 the generation II Pokémon Slowking can be seen on several Hall of Fame posters.
- In episode 4, Jynx is pictured with her original black skin colouration. Since the international release of the generation II games in 2000, the species has been coloured purple due to complaints the character portrayed a racist stereotype with the black skin.
- This is the first Pokemon series in English to not be dubbed in New York City.
- The mega evolution Charizard was a nod from the director to the upcoming games. The show was broadcast on TV Tokyo on October 2, 2013, ten days before the release of the X and Y video games.
- The rival is named Green in the Japanese version, but is called Blue in the English version. This is because the first Pokémon games in Japan were called Red and Green, while the first localized releases were called Red and Blue, due to them being a combination of the Japanese Red, Green, and Blue games. Despite having his name changed in the English version, however, "Blue" still wears a green shirt.
- The beginning of the first episode features sound effects from the original Game Boy games, drawing from the opening animation from Pokémon Red and Green (with a Gengar battling a Nidorino). The main Pokémon anime had also animated the same opening animation in a similar fashion in the beginning of its own first episode, Pokémon - I Choose You!.
- When Red is presented with his Pokédex, his response is "Science is so amazing!" This is also the comment that Ash uses when seeing Clemont's inventions in the main Pokémon anime.
- In the Japanese version of this episode, Red initially considers nicknaming his Charmander Sepultura (meaning "grave" or "burial" in Spanish) prior to his decision of refraining from nicknaming Charmander at all. "Sepultura" is a nickname that was given to a Charmander that appeared in a screenshot on the back of the Japanese box packaging of Pokémon Red.
- When introducing the starter Pokémon, Professor Oak called Bulbasaur a "plant Pokémon" (Japanese: しょくぶつポケモン) instead of a Grass Pokémon, with the terms referring to the types. Despite this apparent oversight, this usage is consistent with Professor Oak's dialogue from the Japanese Pokémon Red, Green, and Blue, international Pokémon Red and Blue, and Japanese Pokémon FireRed and LeafGreen if the player is about to choose Bulbasaur as their starter Pokémon.
- Before Red challenges Brock, the female trainer at the entrance believes Red is "light years away from being ready for that", a rough quote from the first Jr. Trainer♂ encountered in the Pewter Gym from Pokémon Red and Blue.
- all information on Pokemon Origins (Anime) came from http://pokemon.wikia.com/wiki/Pokémon_Origins